Bile Duct Cancer
Bile duct cancer (cholangiocarcinoma) develops in the bile ducts that carry bile from the liver to the small intestine. It is a rare but serious cancer.
Understanding Bile Duct Cancer
Cholangiocarcinoma is classified by location as intrahepatic (within the liver), perihilar (at the junction of the hepatic ducts), or distal (in the common bile duct). Each type presents differently and may require different surgical approaches.
Common Symptoms
- Jaundice
- Itching
- Dark urine and pale stools
- Abdominal pain
- Unexplained weight loss
- Fatigue
How It Is Diagnosed
Diagnosis involves blood tests (liver function, CA 19-9), imaging (MRI/MRCP, CT, endoscopic ultrasound), and biopsy. ERCP may be used for both diagnosis and biliary drainage.
Frequently Asked Questions
Common questions about Bile Duct Cancer
What is the role of molecular testing in bile duct cancer?
Molecular testing can identify targetable mutations such as FGFR2 fusions and IDH1 mutations, for which specific targeted therapies are available. It is recommended for all patients with advanced biliary tract cancer.
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